Deploy Application that requires other apps to be closed.

I have done traditional SCCM deployments.  I'm now experimenting with SCCM 2012 Application Deployment.

I am trying to determine how this will work if the application you want to deploy depends on another application to be closed?  For instance, I am deploying an application that requires Outlook to be closed.

Since Outlook is open during the majority of a person working session, then there needs to be some way to meet this requirement.  How is this achieved?